I have a question regarding entering interaction terms (moderation) in SPSS.

Is there a conceptual difference between entering interaction terms and main effects via direct entry (at the same time) vs hierarchically (in blocks)? I am thinking about this in terms of regression models (specifically logistic regression).

I will be entering two 3-way interactions and their respective lower ordered terms (I have a large enough sample size).

I can only assume that this may impact how the variance is explained, although I can't seem to wrap my head around the distinction.

If i go the route of Multinomial Logistic Regression, it is my assumption the only way to enter all of my interaction terms (and lower ordered terms) is by entering them all at the same time. Is this inaccurate?

Any help would be most appreciated! Also, any references or citations you could provide would also be very helpful!