[UPDATE: In his latest news conference, Clark County Sheriff Joseph Lombardo said that the number of people killed by Stephen Paddock in Las Vegas has risen to 58 with 515 people wounded.] While the Las Vegas shooting is the worst mass shooting in modern American history, it’s not the worst ever, In 1890, the U.S. Cavalry opened fire on the Lakota tribe, killing somewhere between 150 and 300 members. FWIW, 25 soldiers also died at the Wounded Knee Massacre.